Treatment of heart failure and cardiac ischemia-reperfusion injury

摘要

The present invention relates to the use of extracorporeal cardiac shock wave therapy in the treatment or prevention of onset of heart disease, in particular the present invention in (a) treating or preventing heart failure or (b) treating cardiac ischemia reperfusion injury in a subject. Provided is a dipeptidyl peptidase-4 (DPP-4) inhibitor, or a pharmaceutical composition containing said inhibitor, for use, wherein said subject is undergoing extracorporeal cardiac shock wave therapy, said inhibitor comprising: It is administered before, at the same time as, and / or after the shock wave therapy.