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Pharmaceutical patch containing lidocaine and diclofenac for treating neuropathic pain

机译:含有利多卡因和双氯芬酸的药物贴剂,用于治疗神经性疼痛

摘要

The present invention relates to a medicated patch comprising a lidocaine component and a diclofenac component for local use in the local treatment or prevention of pain, wherein the relative weight ratio of the lidocaine component to the diclofenac component is non-constituent of lidocaine. Is in the range of about 7: 1 to about 4: 1 based on the equivalent of the salt form and the equivalent of the non-salt form of diclofenac, wherein the pain is neuropathic pain or the pain is The present invention relates to a medicated patch having an element. The pharmaceutical composition is suitable for topical administration, via the delivery of lidocaine and diclofenac to the skin, and in some cases also through the skin to other deeper tissues such as synovial fluid. Suitable for imparting local pharmacological effects without significant systemic exposure.
机译:本发明涉及用于局部治疗或预防疼痛的局部使用利多卡因组分和双氯芬酸组分的药物贴剂,其中利多卡因组分与双氯芬酸组分的相对重量比是利多卡因的非组成部分。基于双氯芬酸的盐形式和非盐形式的当量,在约7∶1至约4∶1的范围内,其中所述疼痛是神经性疼痛或所述疼痛是指。含元素的药贴。该药物组合物适于通过利多卡因和双氯芬酸向皮肤的递送,并且在某些情况下还通过皮肤至其他更深的组织,例如滑液,进行局部给药。适用于在不引起大量全身暴露的情况下赋予局部药理作用。

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