首页> 外国专利> N1- (4- (5- (cyclopropylmethyl) -1-methyl-1H-pyrazol-4-yl) pyridin-2-yl) cyclohexane-1 as CK1 and / or IRAK1 inhibitor for treating cancer , 4-Diamine derivatives and related compounds

N1- (4- (5- (cyclopropylmethyl) -1-methyl-1H-pyrazol-4-yl) pyridin-2-yl) cyclohexane-1 as CK1 and / or IRAK1 inhibitor for treating cancer , 4-Diamine derivatives and related compounds

机译:N1-(4-(5-(环丙基甲基)-1-甲基-1H-吡唑-4-基)吡啶-2-基)环己烷-1作为CK1和/或IRAK1抑制剂,用于治疗癌症,4-二胺衍生物及相关药物化合物

摘要

Abstract: The present invention provides a compound of formula (I) as a casein kinase 1 (CK1) and / or interleukin 1 receptor-related kinase 1 (IRAKI) inhibitor for treating cancer, inflammatory disorders, and immune-related disorders. Pyrazole derivatives of I), especially N1- (4- (5- (cyclopropylmethyl) -1-methyl-1H-pyrazol-4-yl) pyridin-2-yl) cyclohexane-1,4-diamine derivatives and related Compounds are provided. [Chemical 1] [Selection diagram] None
机译:摘要:本发明提供式(I)的化合物作为酪蛋白激酶1(CK1)和/或白介素1受体相关激酶1(IRAKI)抑制剂,用于治疗癌症,炎性疾病和免疫相关疾病。提供了I)的吡唑衍生物,特别是N1-(4-(5-(环丙基甲基)-1-甲基-1H-吡唑-4-基)吡啶-2-基)环己烷-1,4-二胺衍生物和相关化合物。 [化学1] [选择图]无

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