Methods and systems for three-dimensional thickness mapping of corneal microlayers and corneal diagnostics

摘要

Techniques for improved diagnosis, treatment, and monitoring of corneal lesions use improved mapping of the cornea or corneal area, while maintaining specific corneal microlayer thickness data, Develop a mapping. The registration of the segmentation of these microlayers uses the identification of the front and back surfaces as well as the measurement of the surface vertices. A 3D heat map and a bullseye map are generated from the resulting thickness data. These maps show keratoconus, pericidian margin degeneration, post-refractive dilatation, spherical cornea, corneal transplant rejection and failed grafts in corneal transplantation, fuchs dystrophy, limbal limb stem cell deficiency, dry eye syndrome, and This resulted in improved assessment and diagnosis of corneal lesions, such as post-corneal collagen cross-linking assessment.