DISCRIMINATION METHOD OF PROGNOSTIC RISK AFTER PANCREATIC TUMOR EXTRACTION OPERATION

摘要

To provide prognostic discrimination methods of pancreatic tumor effective for early diagnosis of pancreatic tumor or definition of malignancy of pancreatic tumor.SOLUTION: Provided is a prognostic discrimination method of pancreatic tumor comprising: a first step of measuring the methylation status of a 5'-side untranslated region or a region including the 5'-side untranslated region and a translated region of a cancer gene and/or a cancer-suppressing gene in a specimen sample derived from a subject; and, in order to discriminate the prognosis of the subject's pancreatic tumor, a second step of substituting a measured value of the methylation status of the 5'-side untranslated region or the region including the 5'-side untranslated region and the translated region of the cancer gene and/or the cancer-suppressing gene obtained in the first step, for the discriminant of a machine learning model using, as a teacher, measurement values obtained by measuring the methylation status of the 5'-side untranslated region or the region including the 5'-side untranslated region and the translated region of the cancer gene and/or the cancer-suppressing gene in a plurality of specimen samples that are known to be a specimen sample derived from tumor tissue or a specimen sample derived from non-tumor tissue.SELECTED DRAWING: None