There is provided an arrangement including an x-ray detector arranged in conjunction with in-line x-ray focusing optics configured for manipulation of x-rays in medical transmission radiography, wherein the in-line x-ray optics includes an array of lenses, in which the lenses cover parts of, or the entire, field of view, and in which the x-ray detector is a photon-counting detector. Furthermore, the x-ray detector is an energy-resolving detector and chromatic aberration of the lens array and/or limited coherence of the source is compensated for by the energy resolution of the energy-resolving detector, and/or the x-ray detector is a depth-resolving detector and chromatic aberration of the lens array and/or limited coherence of the source is compensated for by depth resolution or volumetric resolution in the detector.
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