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Silk Fibroin Tracheal Stent

机译:丝素蛋白气管支架

摘要

Bioresorbable silk fibroin tracheal stents can be designed and engineered to maintain a tracheal opening. A tracheal stent will maintain a tracheal opening for a period while tissue structure and function is restored. Bioresorbable silk fibroin tracheal stents programmably degrade without negative biological or clinical outcomes. Bioresorbable silk fibroin tracheal stents do not need to be removed following tracheal restoration. Bioresorbable biopolymer tracheal stents can be internally or externally deployed. Bioresorbable biopolymer tracheal stents, for example can be internally or externally deployed in a patient. Such stents may be affixed to function as a splint with tunable mechanically properties to treat, for example, a patient with severe airway collapse.
机译:可以设计和制造可生物吸收的丝素蛋白气管支架以维持气管开放。在恢复组织结构和功能的同时,气管支架将保持气管开放一段时间。可生物吸收的丝素蛋白气管支架可程序降解,而没有负面的生物学或临床结果。气管修复后无需去除可生物吸收的丝素蛋白气管支架。可生物吸收的生物聚合物气管支架可以在内部或外部部署。可生物吸收的生物聚合物气管支架例如可在患者体内或体外进行部署。这样的支架可以被固定以用作具有可调的机械特性的夹板,以治疗例如严重气道塌陷的患者。

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