首页> 外国专利> NOVEL QUINAZOLINONES THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE

NOVEL QUINAZOLINONES THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE

机译:抑制Tau低聚物形成的新型喹唑啉酮及其使用方法

摘要

Novel quinazolinones useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceutically acceptable salts of said compounds, processes for the preparation of said compounds, intermediates used in the preparation of said compounds, and pharmaceutical compositions containing said compounds. The invention further relates to methods of use of said compounds, salts of said compounds, and said compositions in treating neurodegenerative diseases and related conditions.
机译:公开了可用作tau低聚物形成的抑制剂的新型喹唑啉酮,其可用于治疗神经退行性疾病和相关病症。本发明还涉及所述化合物的药学上可接受的盐,所述化合物的制备方法,用于制备所述化合物的中间体以及包含所述化合物的药物组合物。本发明进一步涉及所述化合物,所述化合物的盐和所述组合物在治疗神经退行性疾病和相关病症中的用途。

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