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INTRANASAL VECTOR VACCINE AGAINST PORCINE EPIDEMIC DIARRHEA
INTRANASAL VECTOR VACCINE AGAINST PORCINE EPIDEMIC DIARRHEA
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机译:猪传染性腹泻的鼻内疫苗
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摘要
The present invention relates to the field of (vector) vaccines, and especially to a canine distemper virus (CDV) vector comprising a heterologous nucleotide sequence which encodes a porcine epidemic diarrhea virus (PEDV) antigen. Said PEDV antigen is preferably a PEDV spike (S) protein. The viral vector of the present invention is useful for producing an immunogenic composition or vaccine for intranasally immunizing sows, and thereby protecting piglets, suckled by said sows, against the clinical signs associated with a PEDV infection.
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