LACTOBACILLUS HAVING ANTIMICROBIAL EFFECT ON GARDNERELLA VAGINALIS AND CANDIDA ALBICANS

摘要

The present invention relates to a lactobacillus strain having antimicrobial activity against Gardnerella vaginalis and Candida albicans, a culture medium of the strain, and a cell-free supernatant of the strain, and to a antimicrobial composition containing the same, a pharmaceutical composition for preventing or treating Gardnerella vaginalis infection or Candida albicans infection containing the same, a pharmaceutical composition for prevention or treatment of vaginitis containing the same, a health functional food for prevention or ameliorating of vaginitis containing the same, and a quasi-drug composition for prevention or ameliorating of vaginitis containing the same. The Lactobacillus paracasei MG4272 strain in accordance with the present disclosure has excellent antimicrobial activity against Gardnerella vaginalis and Candida albicans, and has excellent acid resistance, bile resistance, autoaggregation ability and epithelial cell adhesion ability and is suitable for probiotics and thus may be used in various ways for the composition of prevention or treatment of Gardnerella vaginalis infection, Candida albicans infection and vaginitis.