首页> 外国专利> MG4288 Lactobacillus MG4288 for the treatment or improvement of vaginitis with antimicrobial effect on Gardnerella vaginalis and Candida albicans

MG4288 Lactobacillus MG4288 for the treatment or improvement of vaginitis with antimicrobial effect on Gardnerella vaginalis and Candida albicans

机译:MG4288乳酸菌MG4288用于治疗或改善阴道炎,并对阴道加德纳菌和白色念珠菌具有抗菌作用

摘要

The present invention relates to a cell-free supernatant of Lactobacillus strains, strain cultures and strains having antimicrobial activity against Gardnerella vaginalis and Candida albicans , guards The present invention relates to a pharmaceutical composition for preventing or treating Nerella Baginalis infection or Candida albicans infection, a pharmaceutical composition for preventing or treating vaginitis, a health functional food for preventing or improving vaginitis, and a quasi-drug composition for preventing or improving vaginitis. The Lactobacillus rhamnosus MG4288 strain of the present invention has excellent antibacterial activity against Gardnerella baginalis and Candida albicans, and is excellent in acid resistance, bile resistance, self-cohesiveness and epithelial cell adhesion, so it is suitable for probiotics, so Nalis infection, Candida albicans infection and vaginitis prevention or treatment composition, etc. can be used in various ways.
机译:本发明涉及乳酸杆菌菌株的无细胞上清液,菌株培养物和对阴道加德纳氏菌和白色念珠菌具有抗微生物活性的菌株,其警卫物技术领域本发明涉及药物。用于预防或治疗Nerella Baginalis感染或白色念珠菌感染的组合物,用于预防或治疗阴道炎的药物组合物,用于预防或改善阴道炎的保健功能食品以及用于预防或改善阴道炎的准药物组合物。本发明的鼠李糖乳杆菌MG4288菌株对巴氏加德纳氏菌和白色念珠菌具有优异的抗菌活性,并且具有优异的耐酸性,耐胆汁性,自粘性和上皮细胞粘附性,因此适用于益生菌,纳利氏菌感染,念珠菌可以多种方式使用白色念珠菌感染和预防或治疗阴道炎的组合物等。

著录项

  • 公开/公告号KR102139687B1

    专利类型

  • 公开/公告日2020-07-30

    原文格式PDF

  • 申请/专利权人 MEDIOGEN CO. LTD.;PAEK NAM SOO;

    申请/专利号KR20190052269

  • 发明设计人 백남수;강창호;

    申请日2019-05-03

  • 分类号C12N1/20;A23L33/135;A61K35/747;A61P15/02;A61P31/04;C12R1/225;

  • 国家 KR

  • 入库时间 2022-08-21 11:04:08

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