tricyclic compounds as inhibitors of histone methyl transferases

摘要

the present invention relates to certain tricyclic compounds that are inhibitors of histone methyltransferases g9a and / or glp and are therefore useful for the treatment of diseases treatable by inhibition of g9a and / or glp such as cancers and hemoglobinopathies (for example, beta-thalassemia and sickle cell disease). pharmaceutical compositions containing such compounds and processes for preparing such compounds are also provided.