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artificial genome manipulation for regulation of gene expression
artificial genome manipulation for regulation of gene expression
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机译:人工基因组操纵调节基因表达
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摘要
the present invention relates to an expression control composition for regulating the expression of repeated genes or a method that uses it. more specifically, the present invention relates to an expression regulation composition comprising a guide nucleic acid with the ability to target the transcriptional regulatory region of repeated genes and a method for regulating the expression of repeated genes using the composition for manipulate and / or artificially modify a transcriptional regulatory region of the repeated genes. in addition, the present invention relates to a method for treating or alleviating a disease caused by gene repetition with the use of an expression control composition to regulate the expression of repeated genes.
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