首页> 外文期刊>Acta Anaesthesiologica Scandinavica >protein, the Cra recognition weight matrix from foot-printing data was developed and used to scan the whole genome. Several new Cra-binding sites were found, and some of the result was consistent with the DNA microarray data. The ED pathway was active in the cra mutant; we constructed cra.edd double genes knockout mutant to block this pathway, where the acetate overflowed due to the down-regulation of aceA,B and icd gene expressions. Then we further constructed cra.edd.iclR triple genes knockout
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protein, the Cra recognition weight matrix from foot-printing data was developed and used to scan the whole genome. Several new Cra-binding sites were found, and some of the result was consistent with the DNA microarray data. The ED pathway was active in the cra mutant; we constructed cra.edd double genes knockout mutant to block this pathway, where the acetate overflowed due to the down-regulation of aceA,B and icd gene expressions. Then we further constructed cra.edd.iclR triple genes knockout

机译:从脚印数据中提取出Cra识别权重矩阵,并将其用于扫描整个基因组。发现了几个新的Cra结合位点,其中一些结果与DNA微阵列数据一致。 ED途径在cra突变体中很活跃。我们构建了craded双基因敲除突变体,以阻断该途径,其中乙酸由于aceA,B和icd基因表达的下调而溢出。然后我们进一步构建了cra.edd.iclR三基因敲除

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