process for preparing a cross-linked biocompatible polysaccharide gel composition, and polysaccharide gel composition.

摘要

"process for preparing a cross-linked biocompatible polysaccharide gel composition, cross-linked biocompatible polysaccharide and polysaccharide gel composition, use of a composition, and, medical or prophylactic treatment process of a mammal". the present invention provides a process for preparing a cross-linked biocompatible polysaccharide gel composition, comprising: forming an aqueous solution of a water-soluble cross-linkable polysaccharide; initiating a crosslinking of said polysaccharide in the presence of a polyfunctional crosslinking agent for it; sterically prevent the crosslinking reaction from being completed before gelation occurs, an activated polysaccharide being obtained; and reintroducing the sterically hindered conditions for said activated polysaccharide, so as to continue crosslinking it to a viscoelastic gel. the invention also provides a gel composition obtainable by such a process, as well as gel compositions for different medical uses.