3. SIRP - architecture of alpha domain or its variants. （Divisional request 201800340）.

摘要

T. P this note; oacute; n introduces architecture and polyacrylate; eacute; pat and amp impregnants; Iacute; se amp regulator; ntilde; ales (SIRP - (x) they are amp; uacut; tiles, for example,If you have already registered, please log in first.One C amp; eacute; Lula cancerosa or one C amp; eacute; Lula de la sistema immune system,Increase the blood sugar of C amp; eacute; Lula Diana, eliminate C amp; eacute; immune cells, such as lymphocyte regulation, eliminate C amp; eacute; cancer cells, and treat diseases (e.g., research and development)C amp; Aacute; NCER; or any combination of CI amp; s; oacute; of a subject. The architecture of sirp-a includes a DL domain from sirp-a to sirp-a variant, which connects to CD47 and M amp; Aacute; s, which is larger than that of wild sirp-a. The baptism of building polar amp; eacute; sirp-a includes a fusion sirp-a DL, which merges with Mon amp; oacute; albumina S amp; eacute; rich people (HSA), which belongs to Fc domain name only,One P amp; eacute; uni amp; impregnation; oacute; n a alumina or pol amp; Iacute; pure polyethylene (PEG). The components provided in this document include (I) a polypropylene and acrylonitrile; eacute; polypropylene and acrylonitrile including a DL variant; Iacute; se amp regulator; ntilde; ales a (sirp-a) and (II) an antibody / P and;