3. SIRP - architecture of alpha domain or its variants. （Divisional request 201800340）

摘要

T. P this note; oacute; n introduces architecture and polyacrylonitrile amphetamine; eacute; pat amp extract; Iacute; se amp regulator; ntilde; ales (sirp-a), which are amp; uacute; tiles, for example,(b) In any case, States parties shall: One C amp; eacute; Lula cancerosa or one C amp; eacute; Lula de la sistema immune system,Increase the blood sugar of C amp; eacute; Lula Diana, eliminate C amp; eacute; immune cells, such as lymphocyte regulation, eliminate C amp; eacute; cancer cells, and treat diseases (e.g., research and development)C amp; Aacute; NCER; or any combination of CI amp; s; oacute; of a subject. The architecture of sirp-a includes a high affinity sirp-a D1 domain or its variants, which combines CD47 with M amp; Aacute; s is higher than that of wild sirp-a. The impregnation of architectural or polypropylene acrylonitrile-amp; eacute; sirp-a includes a variant of sirp-a of type D1, which is combined with Mon amp; oacute; ALB amp; uacute; Mina amp; eacute; Rica (HSA) in FC field only,One P amp; eacute; pfido uni amp; oacute; Na ALB amp; uacute; Mina or un pol amp; Iacute; pure polyethylene (PEG). The components provided in this document include (I) a polypropylene and acrylonitrile; eacute; a D1 variant including protein and acrylonitrile; Iacute; a regulator of Se amp; ntilde; ales a (sirp-a) and (b) an antibody / P and;