首页>
外国专利>
PROCEDURES FOR THE TREATMENT OF INDIVIDUALS WITH PRADER-WILLIS SYNDROME OR SMITH-MAGENIS SYNDROME
PROCEDURES FOR THE TREATMENT OF INDIVIDUALS WITH PRADER-WILLIS SYNDROME OR SMITH-MAGENIS SYNDROME
展开▼
机译:PRADER-WILLIS综合征或Smith-Magenis综合征治疗个体的程序
展开▼
页面导航
摘要
著录项
相似文献
摘要
Provided are immediate or prolonged administration of certain potassium ATP (KATP) channel openers, optionally in combination with growth hormone, to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving KATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of KATP channel openers that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. Further provided are methods of co-administering KATP channel openers with other drugs (e.g., in combination with growth hormone) to treat diseases of humans and animals (e.g., Prader-Willi Syndrome (PWS), Smith-Magenis syndrome (SMS), and the like.
展开▼