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Human monoclonal antibody with specificity for dengue virus serotype 1 e protein and uses thereof
Human monoclonal antibody with specificity for dengue virus serotype 1 e protein and uses thereof
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机译:对登革热病毒血清型1e蛋白具有特异性的人单克隆抗体及其用途
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摘要
Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.
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