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Nmda receptor modulators and prodrugs, salts, and uses thereof

机译:NMDA受体调节剂和前药,盐及其用途

摘要

Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
机译:公开了在NMDA受体活性的调节中具有增强的效力的化合物。预期此类化合物用于治疗疾病和病症,例如学习,认知活动和镇痛,特别是用于减轻和/或减轻神经性疼痛。还公开了化合物的口服可获得的制剂和其他药学上可接受的递送形式,包括静脉内制剂。

著录项

  • 公开/公告号IL245302A

    专利类型

  • 公开/公告日2020-05-31

    原文格式PDF

  • 申请/专利权人 NAUREX INC.;

    申请/专利号IL20160245302

  • 发明设计人

    申请日2016-04-25

  • 分类号A61K38/12;A61P25/18;A61P25/28;C07K5/10;C07K5/12;C07K7/56;

  • 国家 IL

  • 入库时间 2022-08-21 11:17:18

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