首页> 外国专利> Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria

Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria

机译：链球菌噬菌体溶素用于革兰氏阳性菌的检测和治疗

页面导航

摘要
著录项
相似文献

摘要

The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus , and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided.

机译：本发明提供了可用于预防和治疗改善和治疗革兰氏阳性细菌（包括链球菌和葡萄球菌）以及相关病症的方法，组合物和制品。本发明提供了掺入和利用猪链球菌衍生的噬菌体溶素，特别是PlySs2和/或PlySs1裂解酶及其变体，包括其截短的组合物和方法。提供了治疗人类的方法。

著录项

公开/公告号IL266476A

专利类型
公开/公告日2020-01-30

原文格式PDF
申请/专利权人 THE ROCKEFELLER UNIVERSITY;
展开▼

申请/专利号IL20190266476
发明设计人
展开▼

申请日2019-05-06
分类号A61K38/16;A61K38/46;A61K38/47;A61K38/50;A61K45/06;A61P31/04;C12N9/36;
国家 IL
入库时间 2022-08-21 11:17:15

相似文献

专利
外文文献
中文文献

1. Green Fluorescent Protein Recombinant Nisin as a Probe for Detection of Gram-Positive Bacteria [J] . Xiqian Tan, Ye Han, Huazhi Xiao, 天津大学学报（英文版） . 2017,第004期

2. Comparison of the serum contents of inflammatory mediators and oxidative stress mediators between patients with gram-positive bacteria and gram-negative bacteria infection [J] . Yu-Qing Hao, Fang Chen, Li-Sha Jiang, 海南医科大学学报（英文版） . 2017,第022期

3. Comparison of the serum contents of inflammatory mediators and oxidative stress mediators between patients with gram-positive bacteria and gram-negative bacteria infection [J] . Yu-Qing Hao, Fang Chen, Li-Sha Jiang, 海南医科大学学报(英文版) . 2017,第022期

4. Implementation of a Rapid Microarray Assay for the Detection of Gram-Positive, Gram-Negative and Resistance Determinants： Assessing Performance in a Clinical Laboratory in Bulgaria [J] . Encho Savov, Angelina Trifonova, Iva Todorova, 药剂与药理学：英文版 . 2015,第006期

5. Bacteriolysis and Inhibition of Gram-Positive Bacteria by Components of Streptococcus zymogenes Lysin [J] . Robert W. Jackson Journal of bacteriology . 1971,第1期

6. Corrigendum: Bacteriophages and bacteriophage‐derived endolysins as potential therapeutics to combat Gram‐positive spore?forming bacteria [J] . Nakonieczna A., Cooper C.J., Gryko R. Journal of applied microbiology . 2018,第6期

7. Bacteriophages and bacteriophage-derived endolysins as potential therapeutics to combat Gram-positive spore forming bacteria [J] . Nakonieczna A., Cooper C. J., Gryko R. Journal of applied microbiology . 2015,第3期

8. 3D Structure of the Long Fimbriae of the Gram-Positive Bacteria Streptococcus parasanguinis [C] . Chul Ho Park, Carsten Peters, Michael Radermacher, Microscopy and microanalysis.;Microscopy and microanalysis. . 2010

9. Bacteriophage SeP9 of Streptococcus equi and the antibacterial activity of its lysin. [D] . Tiwari, Raksha. 2007

10. TSPphg Lysin from the Extremophilic Thermus Bacteriophage TSP4 as a Potential Antimicrobial Agent against Both Gram-Negative and Gram-Positive Pathogenic Bacteria [O] . Feng Wang, Xinyu Ji, Qiupeng Li, 2020

11. TSPphg Lysin from the Extremophilic Thermus Bacteriophage TSP4 as a Potential Antimicrobial Agent against Both Gram-Negative and Gram-Positive Pathogenic Bacteria [O] . Feng Wang, Xinyu Ji, Qiupeng Li, 2020

1. Study on Enhanced Antibacterial and Cytotoxicity of Pure and Cadmium Doped Cerium Oxide against Gram-Positive and Gram-Negative Bacteria [J] . Killivalavan Govindarasu ,Kavitha Gnanasekaran ,Sathyaseelan Balaraman . 软纳米科学报（英文） . 2019,第1期

2. 革兰氏阳性菌的病毒--猪链球菌噬菌体的分离与鉴定 [C] . 马玉玲 ,陆承平 . 中国畜牧兽医学会第一届中国养猪生产和疾病控制技术大会 . 2005

3. 噬菌体内溶素在耐甲氧西林金黄色葡萄球菌检测与治疗中的应用研究 [A] . 王映然 . 2020