首页> 外国专利> METHOD FOR PRODUCING A COMPOSITION COMPRISING A 3-O-p-COUMAROYL ESTER OF TORMENTIC ACID FROM A PLANT CELL CULTURE, APPLICATIONS THEREOF AS ANTIPARASITIC AGENT FOR THE TREATMENT OF TRYPANOSOMIASIS

METHOD FOR PRODUCING A COMPOSITION COMPRISING A 3-O-p-COUMAROYL ESTER OF TORMENTIC ACID FROM A PLANT CELL CULTURE, APPLICATIONS THEREOF AS ANTIPARASITIC AGENT FOR THE TREATMENT OF TRYPANOSOMIASIS

机译：从植物细胞培养物中制备含有抗坏血酸的3-O-对-香豆酰基酯的组合物的方法，其作为抗疟疾剂用于治疗锥虫病

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摘要

The present invention relates to a method for the production of a (poly)hydroxylated pentacyclic triterpene composition including a 3-O-p- coumaroyl ester of tormentic acid from a plant suspension cell culture, to a pharmaceutical composition comprising at least 3-O-p-coumaroyl ester of tormentic acid for a use in the prevention and/or the treatment of trypanosomiasis, optionally in admixture with other (poly)hydroxylated pentacyclic triterpenes, and to 3-O-p-coumaroyl ester of tormentic acid for its use as an antiparasitic agent for the prevention and/or the treatment of trypanosomiasis, optionally in admixture with other (poly)hydroxylated pentacyclic triterpenes.

机译：本发明涉及一种从植物悬浮细胞培养物中生产包含聚草酸的3-Op-香豆酰基酯的（多）羟基化的五环三萜组合物的方法，以及包含至少3-Op-香豆酰基酯的药物组合物的方法。用于预防和/或治疗锥虫病的草酸，可选地与其他（多）羟基化的五环三萜类化合物混合使用;以及草酸的3-Op-香豆酰基酯，用作其预防的抗寄生虫药和/或锥虫病的治疗，可选地与其他（多）羟基化的五环三萜混合使用。

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公开/公告号LU101117B1

专利类型
公开/公告日2020-08-07

原文格式PDF
申请/专利权人 LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST);UNIVERSITÉ CATHOLIQUE DE LOUVAIN;
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申请/专利号LU20190101117
发明设计人 ANDRÉ CHRISTELLE;LECLERCQ JOËLLE;LEGAY SYLVAIN;BEAUFAY CLAIRE;CATTEAU LUCY;
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申请日2019-02-07
分类号A01H4;A61K31/56;A61K36/185;A61K36/73;A61P33/02;C07J63;C12N5/04;
国家 LU
入库时间 2022-08-21 11:17:04

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