PHARMACEUTICAL COMPOSITION WITH ANALGESIC, ANTI-INFLAMMATORY, AND THROMBOLYTIC ACTIVITY.

摘要

The present invention relates to the use of pharmaceutical compositions of purified acetone extracts of Bougainvillea X Buttiana Holttum Anda Standl (pink variety), biologically active as an analgesic, anti-inflammatory and thrombolytic. Said composition includes A) collecting and drying the flowers and bracts, B) subjecting the dry and cleaning plant material to crushing until a powder is obtained, and C) subjecting the powder to treatment at 26°C and for 24 hours for two periods with 100% acetone. Also, it involves D) removing the solvent to a certain degree of concentration, E) sowing on a column with 60-200 Mesh silica gel, and F) eluting with a mobile phase of increasing dichloromethane polarity to methanol and with a final wash of the column with distilled water. Further, it includes G) mobile phase and obtaining the fractions, H) monitoring fractions, I) testing each fraction separately to determine analgesic, anti-inflammatory, and thrombolytic activity, and H) Squealing.