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Engineering a control drug release profile via liposome compositions in both aqueous and non-aqueous compartments
Engineering a control drug release profile via liposome compositions in both aqueous and non-aqueous compartments
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机译:通过脂质体组合物在水性和非水性隔室中设计对照药物的释放曲线
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摘要
The present invention relates to a pharmaceutical composition comprising at least one liposome, at least one polyvalent counterion donor or a pharmaceutically acceptable salt thereof, at least one monovalent counterion donor or a pharmaceutically acceptable salt thereof, and an amphipathic therapeutic agent. The pharmaceutical composition exhibits a balance between optimal anti-cancer efficacy and minimal side effects, such as skin toxicity. The present invention also relates to methods of inhibiting cancer cell growth, comprising administering the pharmaceutical composition described herein.
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