Boron cluster conjugates as purinergic receptor ligands, method of their preparation and use

摘要

The subject of the application are adenosine conjugates of formula 1, formula 2 or formula 3 in which R1 is HO-, CH3 (CH2) nO-, CH3 (CH2) nC (O) O-, H2N-, H2N (CH2) nNH- , CH3 (CH2) nNHC (O) -, R2 is a boron cluster, optionally substituted with -OH or -H, F, Cl, Br or Co, Fe, Cr, Ni, and symbolizes a carbon atom or a -CH or -C group, and 0 a boron atom or a BH group. The application also includes the use of conjugates in medicine.