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STREPTOCOCCUS UBERIS EXTRACT AS AN IMMUNOGENIC AGENT

机译:链球菌UBERIS提取物作为免疫原性制剂

摘要

The present invention relates to an extract of Streptococcus uberis as an immunogenic agent. It also relates to a process for obtaining said agent which comprises incubating a biofilm-producing S. uberis strain to obtain a biofilm and thermally treating the biofilm obtained. It relates also to a pharmaceutical composition comprising teichoic acids, preferably lipoteichoic acids, for use in the prevention and/or treatment of mastitis and/or infections caused by Streptococcus sp. or by biofilm-producing bacteria. The present invention also relates to a vaccine which comprises said immunogenic agent and to said vaccine and immunogenic agent for use in the prevention and/or treatment of infections caused by Streptococcus sp., especially in the prevention and/or treatment of mastitis caused by S. uberis. It also relates to a vaccination kit which comprises said agent or vaccine.
机译:本发明涉及作为免疫原性剂的乳房链球菌提取物。它还涉及获得所述试剂的方法,该方法包括孵育产生生物膜的乳房链球菌菌株以获得生物膜,并对所得生物膜进行热处理。本发明还涉及用于预防和/或治疗由链球菌属sp引起的乳腺炎和/或感染的药物组合物,其包含硫磷酸,优选脂磷壁酸。或通过产生生物膜的细菌。本发明还涉及包含所述免疫原性试剂的疫苗,以及涉及所述疫苗和免疫原性试剂,其用于预防和/或治疗由链球菌属引起的感染,特别是用于预防和/或治疗由S引起的乳腺炎。乳房它还涉及包含所述试剂或疫苗的疫苗接种试剂盒。

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