LIVE VIRUS HAVING A BANK OF DENGUE VIRUS ATTENUATED STRAINS, AND A DENGUE VACCINE CONTAINING SAME AS ANTIGENS

摘要

A highly safe dengue vaccine was invented that induced a neutralizing antibody response against all of the four serotypes of dengue virus without developing more than a fixed level of viremia with single administration. A tetravalent dengue virus formulation is provided that is excellent in both efficacy (neutralizing antibody response) and safety (viremia).