首页> 外国专利> COMBINATION OF ANTI-PD-1 ANTIBODIES AND BISPECIFIC ANTI-CD20/ANTI-CD3 ANTIBODIES TO TREAT CANCER

COMBINATION OF ANTI-PD-1 ANTIBODIES AND BISPECIFIC ANTI-CD20/ANTI-CD3 ANTIBODIES TO TREAT CANCER

机译:抗PD-1抗体和双特异性抗CD20 /抗CD3抗体联合治疗癌症

摘要

The present invention provides methods for treating, reducing the severity, or inhibiting the growth of cancer (e.g., a B-cell cancer such as Hodgkin's lymphoma or acute lymphoblastic leukemia). The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of an antibody or antigen-binding fragment thereof that specifically binds to programmed death 1 (PD-1) receptor in combination with a therapeutically effective amount of a bispecific antibody that specifically binds to CD20 and CD3.
机译:本发明提供了用于治疗,降低癌症的严重性或抑制其生长的方法,所述癌症(例如,B细胞癌,如霍奇金淋巴瘤或急性淋巴细胞白血病)。本发明的方法包括与治疗有效量的双特异性抗体组合,向有需要的受试者施用治疗有效量的特异性结合程序性死亡1(PD-1)受体的抗体或其抗原结合片段。与CD20和CD3特异性结合的抗体。

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