SELECTIVE INHIBITOR OF EXON 18 AND/OR EXON 21 MUTANT EGFR
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机译:外显子18和/或外显子21突变EGFR的选择性抑制剂
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摘要
An antitumor agent for treating a malignant tumor patient expressing EGFR having at least one mutation selected from the group consisting of G719X mutation of exon 18, E709X mutation of exon 18, and L861X mutation of exon 21, wherein X represents an arbitrary amino-acid residue, the antitumor agent comprising (S)-N-(4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl)acrylamide or a salt thereof.
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