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Method to support the diagnosis of risk of recurrence of colorectal cancer, program and computer system

机译:支持大肠癌复发风险诊断的方法,程序及计算机系统

摘要

PROBLEM TO BE SOLVED: To provide a highly reliable method for assisting diagnosis of recurrence risk of colon cancer regarding various cases of colon cancer.SOLUTION: A method for assisting diagnosis of recurrence risk of colon cancer includes: a measuring process of severally measuring an expression amount of a plurality of genes selected from a first gene group which exists in a region from 18q21 to 18q23 on a long chain of an 18-th chromosome, a plurality of genes selected from a second gene group which exists in a region from 20q11 to 20q13 on a long chain of a 20-th chromosome, and a plurality of genes selected from a third gene group including ANGPTL2, AXL, C1R, C1S, CALHM2, CTSK, DCN, EMP3, GREM1, ITGAV, KLHL5, MMP2, RAB34, SELM, SRGAP2 P1 and VIM, in a biological sample collected from a colon cancer patient; and a process of determining recurrence risk of colon cancer in the patient based on the expression amounts measured in the measuring process.SELECTED DRAWING: None
机译:解决的问题:提供一种用于诊断各种结肠癌复发风险的高度可靠的方法,以帮助诊断结肠癌的复发风险。解决方案:一种辅助诊断结肠癌复发风险的方法,包括:分别测量表达的测量过程选自第18个染色体长链上18q21至18q23区域中的第一个基因组的多个基因的数量,选自20q11至20q11区域中的第二个基因组的多个基因的数量第20个染色体的长链上的20q13,以及选自第三基因组的多个基因,包括ANGPTL2,AXL,C1R,C1S,CALHM2,CTSK,DCN,EMP3,GREM1,ITGAV,KLHL5,MMP2,RAB34,从结肠癌患者采集的生物样品中的SELM,SRGAP2 P1和VIM;以及根据在测量过程中测量的表达量确定患者结肠癌复发风险的过程。

著录项

  • 公开/公告号ES2745718T3

    专利类型

  • 公开/公告日2020-03-03

    原文格式PDF

  • 申请/专利权人 SYSMEX CORPORATION;

    申请/专利号ES20150186777T

  • 申请日2015-09-25

  • 分类号G01N33/574;C12Q1/6886;

  • 国家 ES

  • 入库时间 2022-08-21 11:15:29

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