首页> 外国专利> METHOD FOR SUPPORTING DIAGNOSIS OF RISK OF COLORECTAL CANCER RECURRENCE, PROGRAM AND COMPUTER SYSTEM

METHOD FOR SUPPORTING DIAGNOSIS OF RISK OF COLORECTAL CANCER RECURRENCE, PROGRAM AND COMPUTER SYSTEM

机译:支持诊断大肠癌复发的方法,程序和计算机系统

摘要

Disclosed is a method for supporting a diagnosis of a risk of colorectal cancer recurrence. The method comprises the steps of: performing a first measurement to measure levels of expression of a plurality of genes selected from a first gene group present in a region from 18q21 to 18q23 on a long arm of chromosome 18 in a biological sample collected from a patient with colorectal cancer, a second measurement to measure levels of expression of a plurality of genes selected from a second gene group present in a region from 20q11 to 20q13 on a long arm of chromosome 20, and a third measurement to measure levels of expression of a plurality of genes selected from a third gene group consisting of ANGPTL2, AXL, C1R, C1S, CALHM2, CTSK, DCN, EMP3, GREM1, ITGAV, KLHL5, MMP2, RAB34, SELM, SRGAP2P1, and VIM; and determining the risk of colorectal cancer recurrence of the patient based on results of the first measurement, second measurement and third measurement.
机译:公开了一种用于支持诊断大肠癌复发风险的方法。该方法包括以下步骤:执行第一测量以测量从患者收集的生物样品中选自存在于第18号染色体长臂上18q21至18q23区域中的第一基因组的多个基因的表达水平。结肠直肠癌,第二次测量可测量选自存在于20号染色体长臂上20q11至20q13区域中的第二个基因组的多个基因的表达水平,第三次测量可测量a基因表达水平多个基因选自由ANGPTL2,AXL,C1R,C1S,CALHM2,CTSK,DCN,EMP3,GREM1,ITGAV,KLHL5,MMP2,RAB34,SELM,SRGAP2P1和VIM组成的第三基因组;并根据第一测量,第二测量和第三测量的结果确定患者结直肠癌复发的风险。

著录项

  • 公开/公告号EP3009842B1

    专利类型

  • 公开/公告日2019-09-04

    原文格式PDF

  • 申请/专利权人 SYSMEX CORPORATION;

    申请/专利号EP20150186777

  • 申请日2015-09-25

  • 分类号G01N33/574;C12Q1/6886;

  • 国家 EP

  • 入库时间 2022-08-21 12:31:04

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