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CROSS-LINKED POLY-E-LYSINE NON-PARTICULATE SUPPORT

机译:交联聚赖氨酸非颗粒状支持

摘要

The invention provides a non-particulate cross-linked poly-e-lysine polymer. The poly-e-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-e-lysine. The polymer is suitably insoluble in water and other solvents and is provided in macro form for example a sheet, article or fibre. The macro form polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilisation of species, cell culturing and in chromatographic separation.
机译:本发明提供了一种非颗粒交联的聚-赖氨酸聚合物。聚-赖氨酸和交联剂通过酰胺键连接,并且交联剂可以具有至少两个能够与聚-赖氨酸的α碳胺反应的官能团。该聚合物合适地不溶于水和其他溶剂,并以宏观形式提供,例如片,制品或纤维。所述大分子形式的聚合物可用于包括伤口治疗在内的广泛应用,作为医学诊断剂,其包含颗粒状载体和通过所述载体结合或保留的功能材料,以及肽,寡核苷酸,寡糖,物种固定,细胞的固相合成。培养和色谱分离。

著录项

  • 公开/公告号CA2833589C

    专利类型

  • 公开/公告日2020-03-24

    原文格式PDF

  • 申请/专利权人 SPHERITECH LTD;

    申请/专利号CA20122833589

  • 发明设计人 WELLINGS DONALD;

    申请日2012-04-20

  • 分类号C08G69/48;A61K49/18;A61L15/32;C08J3/24;C12N11/02;

  • 国家 CA

  • 入库时间 2022-08-21 11:15:08

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