首页> 外国专利> 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES, METHODS FOR PREPARING SAME, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF

1,4-DISUBSTITUTED 1,2,3-TRIAZOLES, METHODS FOR PREPARING SAME, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF

机译:1,4-二取代的1,2,3-三唑,其制备方法及其诊断和治疗用途

摘要

The present invention relates to a compound of the following general formula (I): (see formula I) in which : - X represents a nitrogen atom and Y represents a carbon atom; or - X represents a carbon atom and Y represents a nitrogen atom; the Ar group represents an aryl or heteroaryl group; and - the groups RN and RN 'form together, with the carbon atom to which they are linked, a mono- or bicyclic azacycloalkane group; as well as its pharmaceutically acceptable salts, hydrates or structures polymorphic crystalline, its racemates, diastereomers or enantiomers. The compounds according to the invention may prove useful for diagnosing or treat them pathologies such as cognitive disorders, pain, and addiction to tobacco.
机译:本发明涉及以下通式(I)的化合物:(参见式I)其中:-X代表氮原子,Y代表碳原子;或-X表示碳原子,Y表示氮原子。 Ar基团表示芳基或杂芳基; -RN和RN'基团与它们连接的碳原子一起形成单环或双环氮杂环烷烃基;以及其药学上可接受的盐,水合物或多晶型结构,其外消旋物,非对映异构体或对映异构体。本发明的化合物可被证明可用于诊断或治疗它们的病状,例如认知障碍,疼痛和烟草成瘾。

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