USE OF A GENETICALLY MODIFIED INFECTIOUS MEASLES VIRUS WITH ENHANCED PRO-APOPTOTIC PROPERTIES (MV-DELTAC VIRUS) IN CANCER THERAPY

摘要

The invention relates to a genetically modified infectious measles virusderived from a live-attenuated measles virusstrain, in which the gene encoding the viral accessory C protein has beenknocked out (MV-deltaC). It concerns in particular the useof said genetically modified infectious MV-deltaC in the treatment ofmalignant tumour or cancer conditions, and for the preparationof agents or compositions for such treatment.