MULTIVALENT IMMUNOGENIC COMPOSITION COMPRISING POLYSACCHARIDE-PROTEIN CONJUGATES, AND VACCINE COMPRISING SAME FOR PREVENTING DISEASE CAUSED BY STREPTOCOCCUS PNEUMONIAE

摘要

The present invention relates to a multivalent immunogenic composition comprising Streptococcus pneumoniae polysaccharide-protein conjugates, and a pharmaceutical composition comprising same. The multivalent immunogenic composition according to one aspect of the present invention comprises a physiologically acceptable vehicle and 15 different polysaccharide-carrier protein conjugates, wherein each of the polysaccharide-protein conjugates comprises a Streptococcus pneumoniae-derived capsular polysaccharide of a different serum type attached to a carrier protein, the capsular polysaccharide being produced from serum types of 1, 3, 4, 5, 6A, 6B, 7F, 9V, 11A, 14, 18C, 19A, 19F, 22F, and 23F.