NEW USE OF CARBAMATE β PHENYLETHANOLAMINE ANALOGUES FOR ENHANCING INTRACELLULAR CLEARANCE OF LDL CHOLESTEROL AND FOR COMBINING THERAPY WITH STATINS TO ENHANCE THE EFFICACY AND REDUCE ADVERSE EFFECTS

摘要

The invention related to the use of carbamate-β- phenylethanolamine analogues for up-regulating of LDL receptors, facilitating uptake of extracellular LDL cholesterol and reducing intercellular total cholesterol. It also related to use of carbamate-β- phenylethanolamine analogues and statins or other lipid lowering agents as combined therapies for synergic effects in lowering LDL cholesterol as well as for reducing adverse effects.