首页> 外国专利> PHARMACOGENOMIC SCREENING METHOD FOR ANTICIPATING A PATIENT'S RESPONSE TO THE TREATMENT OF OCULAR HYPERTENSION

PHARMACOGENOMIC SCREENING METHOD FOR ANTICIPATING A PATIENT'S RESPONSE TO THE TREATMENT OF OCULAR HYPERTENSION

机译:药物基因组学筛查方法,用于治疗患者对眼部高压症的反应

摘要

The present invention discloses a pharmacogenomic screening method for anticipating a patient's response to the treatment of ocular hypertension, comprising the steps of: (a) obtaining a sample of a biological fluid from a patient; and (b) determining the number of copies of an intronic portion of gene MLIP (MLIP-AS1), wherein more than one copy of said MLIP-AS1 is an indication that the patient is a better responder to treatment with prostaglandins, and wherein less than one copy of said MLIP-AS1 is an indication that the patient responds to treatment with β-blockers.
机译:本发明公开了一种用于预测患者对高眼压治疗的反应的药物基因组学筛选方法,包括以下步骤:(a)从患者获得生物流体的样品; (b)确定基因MLIP(MLIP-AS1)的内含子部分的拷贝数,其中多于一个拷贝的所述MLIP-AS1表明患者是对前列腺素治疗更好的反应者,并且其中较少所述MLIP-AS1的一个拷贝的多于一个表示患者对β-受体阻滞剂的治疗有反应。

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