PHARMACOGENOMIC SCREENING METHOD FOR ANTICIPATING A PATIENT'S RESPONSE TO THE TREATMENT OF OCULAR HYPERTENSION

摘要

The present invention discloses a method for in vitro screening of a patient's response to the treatment of ocular hypertension, comprising the steps of: (a) obtaining a sample of a biological fluid from a patient; and (b) determining the number of copies of an intronic portion of gene MLIP (MLIP-AS1), wherein more than one copy of said MLIP-AS1 is an indication that the patient is better responder to the treatment with prostaglandins, and wherein less than one copy of said MLIP-AS1 is an indication that the patient is responder to the treatment with β-blockers.