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PREPARATION METHOD FOR SOLUTION CONTAINING FRUCTOSE SODIUM DIPHOSPHATE, USE THEREOF, AND PREPARATION METHOD FOR SODIUM FRUCTOSE DIPHOSPHATE INJECTION
PREPARATION METHOD FOR SOLUTION CONTAINING FRUCTOSE SODIUM DIPHOSPHATE, USE THEREOF, AND PREPARATION METHOD FOR SODIUM FRUCTOSE DIPHOSPHATE INJECTION
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机译:含有果糖二磷酸钠的溶液的制备方法,其用途以及注射果糖二磷酸钠的制备方法
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摘要
Provided are a preparation method for a solution containing fructose sodium diphosphate, use thereof, and a preparation method for a fructose sodium diphosphate injection. The preparation method for the solution containing fructose sodium diphosphate comprises performing solid-liquid separation on a yeast reaction solution containing fructose sodium diphosphate, anion exchange resin extraction, decolorization, reverse osmosis treatment and sterilization treatment. The yeast reaction solution is obtained by contacting a sugar-containing material containing glucose and phosphoric acid with yeast. Other dosage forms such as fructose sodium diphosphate injections or fructose sodium diphosphate oral solutions can be further prepared using said method. The preparation method has advantages of greatly reducing the dosage of an organic solvent and reducing the production cost.
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