PREDICTION OF HCV-RELATED HCC RECURRENCE BY EXOSOMAL LNC-DANCR LEVELS

摘要

Long non-coding DANCR (lnc-DANCR) as biomarker for the diagnosis, prognosis and monitor of cancer, including but not limited to hepatocellular carcinoma (HCC) is provided herein. In some embodiments, the method of evaluating the prognosis of hepatocellular carcinoma (HCC) in a subject comprises: isolating at least one transcript of lnc-DANCR from a biological sample of a subject; measuring the test expression level of the at least one transcript of lnc-DANCR; and evaluating the prognosis of hepatocellular carcinoma of the subject according to the comparison of the test expression level to a control expression level of the at least one transcript of lnc-DANCR. In some embodiments, a kit for evaluating the prognosis of hepatocellular carcinoma (HCC) in a subject comprises binding molecules to at least one transcript of lnc-DANCR, wherein the at least one transcript of lnc-DANCR is exosomal lnc-DANCR.