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GENETICALLY MODIFIED CLOSTRIDIUM BACTERIA, PREPARATION AND USES OF SAME

机译:遗传修饰的梭菌细菌,其制备和用途

摘要

The present invention concerns the genetic modification of bacteria of the Clostridium genus, typically solventogenic bacteria of the Clostridium genus, in particular bacteria having, in the wild state, a gene coding an amphenicol-O-acetyltransferase. It thus concerns methods, tools and kits allowing such a genetic modification, in particular the elimination or modification of a sequence coding or controlling the transcription of an amphenicol-O-acetyltransferase, the genetically modified bacteria obtained and the uses of same, in particular for producing a solvent, preferably on an industrial scale.
机译:本发明涉及Clostridium属细菌的遗传修饰,通常是Clostridium属溶剂致菌的细菌,特别是在野生状态下具有编码氨酚-O-乙酰基转移酶。因此,本发明涉及允许进行此类遗传修饰,特别是消除或修饰编码或控制氨苄-O-乙酰转移酶转录的序列的方法,工具和试剂盒,获得的遗传修饰细菌及其用途,特别是用于最好以工业规模生产溶剂。

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