GENETICALLY MODIFIED CLOSTRIDIUM BACTERIA, PREPARATION AND USES THEREOF

摘要

The present invention relates to the genetic modification of bacteria of the genus Clostridium, typically of solventogenic bacteria of the genus Clostridium, in particular of bacteria possessing in the wild a gene coding for an amphenicol-O -acetyltransferase. It thus relates to methods, tools and kits allowing such a genetic modification, in particular the elimination or the modification of a sequence coding or controlling the transcription of an amphenicol-O-acetyltransferase, the genetically modified bacteria obtained and their uses, in particular to produce a solvent, preferably on an industrial scale.