首页> 外国专利> IMMUNOPOTENTIATING OR ANTICANCER ACTIVITY-AUGMENTING COMPOSITION COMPRISING MAL-EXPRESSED STEM CELL LIKE MEMORY T CELL AS ACTIVE INGREDIENT

IMMUNOPOTENTIATING OR ANTICANCER ACTIVITY-AUGMENTING COMPOSITION COMPRISING MAL-EXPRESSED STEM CELL LIKE MEMORY T CELL AS ACTIVE INGREDIENT

机译:免疫性或抗肿瘤活性增强组合物,包含与记忆T细胞类似的恶意表达干细胞作为活性成分

摘要

The present invention relates to an immunopotentiating or anticancer activity-augmenting composition comprising MAL-expressed, stem cell like memory T cells as an active ingredient. According to the present invention, myelin and lymphocyte (MAL) augments the differentiation, viability, and activity of stem cell like memory cells (Tscm) and MAL-expressed Tscm can be utilized in an immunopotentiating or anticancer activity-augmenting composition. MAL can be advantageously used in a composition for cancer immunotherapy, a composition for induction of Tscm differentiation, a method for screening a cancer immunotherapy agent, a method for screening a Tscm differentiation inducing agent, etc.
机译:本发明涉及一种免疫增强或抗癌活性增强组合物,其包含MAL表达的干细胞样记忆T细胞作为活性成分。根据本发明,髓磷脂和淋巴细胞(MAL)增强了干细胞样记忆细胞(Tscm)的分化,存活力和活性,并且MAL表达的Tscm可用于免疫增强或抗癌活性增强组合物中。 MAL可以有利地用于癌症免疫疗法的组合物,用于诱导Tscm分化的组合物,用于筛选癌症免疫治疗剂的方法,用于筛选Tscm分化诱导剂的方法等。

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