首页> 外国专利> RECOMBINANT STRAINS AND MEDIUM FORMULATION FOR ENHANCING SECRETION TITER USING A TYPE III SECRETION SYSTEM

RECOMBINANT STRAINS AND MEDIUM FORMULATION FOR ENHANCING SECRETION TITER USING A TYPE III SECRETION SYSTEM

机译：使用III型分泌系统增强分泌滴度的重组菌株和培养基配方

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摘要

The present disclosure provides a recombinant Salmonella strain having a Type III secretion system (T3SS) comprising mutation which enhance protein expression and production. Additionally, methods and kits for using the recombinant Salmonella strain for producing a protein of interest are provided. Additionally, an optimized medium that increases protein expression in a Salmonella strain having a Type III secretion system (T3SS) is provided.

机译：本公开内容提供了具有III型分泌系统（T3SS）的重组沙门氏菌菌株，所述T3SS包含增强蛋白质表达和产生的突变。另外，提供了使用重组沙门氏菌菌株生产目的蛋白的方法和试剂盒。另外，提供了优化的培养基，该培养基可提高具有III型分泌系统（T3SS）的沙门氏菌菌株中的蛋白质表达。 展开▼

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公开/公告号WO2020150533A1

专利类型

公开/公告日2020-07-23

原文格式PDF

申请/专利权人 NORTHWESTERN UNIVERSITY;
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申请/专利号WO2020US13963

发明设计人 TULLMAN-ERCEK DANIELLE;BURDETTE LISA A.;WONG HAN TENG;
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申请日2020-01-16

分类号C07K14/255;C07K14/24;C12N1/36;

国家 WO

入库时间 2022-08-21 11:10:09

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