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SCAN-LESS CONFOCAL MICROSCOPE WITH HIGH RESOLUTION RELATED APPLICATIONS

机译:具有高分辨率的无扫描共聚焦显微镜

摘要

Devices, systems and methods are described that can be used to develop confocal microscopes with high lateral resolution. One example confocal microscope includes a first dispersion element that receives a light beam and to produce illumination beams with different spectral components, and an objective that receives reflected light upon reflection of the illumination beams from a target. The confocal microscope further includes a second dispersion element that receives the reflected light after propagation through the objective lens, and a third dispersion element that receives the dispersed light associated with the second dispersion element and provides an output light to a camera lens for focusing onto a detector. The second and the third dispersion elements are positioned such that each point on the detector is conjugate to a corresponding single point on the target. Some applications of the disclosed confocal microscopes include skin disease diagnosis and imaging of freshly-excised tissues.
机译:描述了可用于开发具有高横向分辨率的共聚焦显微镜的设备,系统和方法。一个示例共聚焦显微镜包括:第一分散元件,其接收光束并产生具有不同光谱成分的照明束;以及物镜,其在来自目标的照明束反射时接收反射光。共聚焦显微镜还包括第二色散元件,第三色散元件接收在传播通过物镜之后的反射光,以及第三色散元件,该第三色散元件接收与第二色散元件相关联的色散光,并将输出光提供给相机镜头,以聚焦到物镜上。探测器。第二和第三色散元件的位置应使检测器上的每个点与目标上相应的单个点共轭。所公开的共聚焦显微镜的一些应用包括皮肤疾病诊断和新鲜切除的组织的成像。

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