METHODS AND SYSTEMS FOR PROTEOMIC PROFILING AND CHARACTERIZATION

摘要

Provided herein are methods and systems for identifying and characterizing proteins, in particular cell surface proteins, of different cell types at the single-cell level. Also provided are methods and systems for distinguishing cells by their protein expression profiles. Further, methods and systems to quantitate and characterize proteins in single cells at ultrahigh throughput are provided. The methods and systems provided herein are able to sensitively profile all epitopes in a proteome of a single cell.