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-35- Injection or eye drops in which indirubin is solubilized using glacial acetic acid and polyoxy-35-castor oil and manufacturing method the same
-35- Injection or eye drops in which indirubin is solubilized using glacial acetic acid and polyoxy-35-castor oil and manufacturing method the same
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机译:-35-使用冰醋酸和聚氧-35-蓖麻油增溶靛玉红的注射剂或滴眼剂及其制造方法
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摘要
The present invention provides injection or eye drop solution in which indirubin is solubilized using glacial acetic acid and polyoxy-35-castor oil and a method for producing the same. The producing method includes: a step of extracting indirubin using glacial acetic acid from Indigo pulverata levis; a step of diluting the glacial acetic acid and precipitating indirubin from the glacial acetic acid; a step of dissolving the indirubin by mixing glacial acetic acid and polyoxy-35-castor oil in the precipitated indirubin; and a step of adding amino acid and purified water to the indirubin and forming a formulation. By the above, the injection or eye drop solution in which indirubin is solubilized can be obtained using glacial acetic acid and polyoxy-35-castor oil to maintain the uniformity of a formulation, has no stimulus on a human body, and prevents reprecipitation by a temperature when indirubin with low solubility to water and ethanol is solubilized in glacial acetic acid and administered to a human body.
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