首页> 外国专利> MCT4 Uses of MCT4 for Diagnosing Peritoneal Metastasis

MCT4 Uses of MCT4 for Diagnosing Peritoneal Metastasis

机译:MCT4 MCT4在诊断腹膜转移中的用途

摘要

The present invention relates to a pharmaceutical composition for treating or inhibiting metastasis of cancer, including an inhibitor or activity inhibitor of MCT as an active ingredient, a food composition for preventing or improving cancer, and a sensitizer for enhancing sensitivity to anticancer agents. Appropriate compositions, wherein MCTs inhibitors, such as siRNAs and / or drugs that inhibit the expression of MCTs of the present invention, reduce the level of proliferation and lactate uptake of cancer cells, thereby reducing the effects of cancer-specific therapeutics and / or other anticancer therapies. It can be usefully used as a sensitizer for doubling.
机译:本发明涉及用于治疗或抑制癌症转移的药物组合物,包括MCT的抑制剂或活性抑制剂作为有效成分,用于预防或改善癌症的食品组合物,以及用于增强对抗癌剂的敏感性的敏化剂。合适的组合物,其中MCTs抑制剂(例如siRNA和/或抑制本发明MCT表达的药物)降低癌细胞的增殖水平和乳酸摄取,从而降低癌症特异性疗法和/或其他药物的作用抗癌疗法。它可以有效地用作增敏剂。

著录项

  • 公开/公告号KR102049812B1

    专利类型

  • 公开/公告日2019-11-28

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20160085613

  • 发明设计人 강원기;이인경;이지연;

    申请日2016-07-06

  • 分类号A61K48;A23L1/30;A61K31/352;A61K31/404;A61K31/519;A61K39/395;A61K41;

  • 国家 KR

  • 入库时间 2022-08-21 11:08:26

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