Recombinant Gallide herpesvirus type 3 vaccine encoding a heterologous avian pathogen antigen

摘要

The present invention relates to a recombinant gallith herpesvirus type 3 vector encoding a heterologous avian pathogen antigen, comprising one or more heterologous polynucleotide (s) inserted in the intergenic loci UL3 / UL4 and / or UL21 / UL22. The present invention also relates to a vaccine comprising said recombinant Galid herpesvirus type 3 vector, optionally an additional Marek's disease viral vector, and to the use of this vaccine to protect avian species against one or more avian pathogens. Do. Additional methods are provided for treating avian species for protection against one or more diseases caused by avian pathogens, and methods for preparing recombinant Galid herpesvirus type 3 vectors encoding heterologous avian pathogen antigens.