Biological tissue model device, blood vessel wall model, blood vessel wall model device, and evaluation method of test substance

摘要

The biotissue model device includes a first liquid compartment for storing a liquid composition; A second liquid compartment for storing the liquid composition; And a cell stack disposed between the first liquid compartment and the second liquid compartment, as a distribution compartment between the two compartments. The vessel wall model includes a porous membrane having a honeycomb structure; A vascular endothelial cell layer disposed on one surface of the porous membrane; And a smooth muscle cell layer or mesenchymal stem cell layer disposed on the other side of the porous membrane. The vessel wall model device includes a first liquid compartment for storing a liquid composition; A second liquid compartment for storing the liquid composition; And a vessel wall model disposed between the first liquid compartment and the second liquid compartment as a distribution compartment between the two compartments. Application of these models or model devices is also provided.